Breast cancer touches the lives of so many women worldwide, yet breast cancer risk and screening needs vary. Genetic testing, risk-assessment tools, and modern imaging can help you and your health care professional build an individualized plan. Screening is a vital tool for catching cancer early, though it cannot guarantee the detection of every case or prevent the disease from developing.

Understanding Your Risk
Risk may be higher because of a harmful gene change linked to cancer risk, a strong family or personal history, prior chest radiation, certain biopsy findings, breast density, or a calculated lifetime risk of about 20% or greater. The American College of Radiology recommends breast cancer risk assessment by age 25 so people at increased risk can begin appropriate screening on time. Ask your provider which validated risk model and guideline apply to you.

Genetic Insight
Genetic testing is most useful when guided by personal and family history and, when appropriate, genetic counseling. Multigene panels may include:

• BRCA1 and BRCA2: Certain gene changes substantially increase breast cancer risk.

• PALB2: Certain gene changes increase breast cancer risk.

• ATM and CHEK2: Some gene changes may moderately increase risk; recommendations depend on the variant and individual history.

A negative test result does not mean your cancer risk is zero because genes are only one part of your overall health. A “variant of uncertain significance” means we do not yet know whether a gene change affects your health, so it should not be treated as a positive result or used alone for major medical decisions. Review your results with your doctor, a geneticist, or a specialized surgeon.

Breast Imaging Options
Mammography remains the primary screening test for most women. 3D mammography improves breast cancer detection and reduces patient callback rates compared to standard 2D mammography. For selected higher-risk patients, breast MRI may be added. Ultrasound, contrast-enhanced mammography, or molecular breast imaging may be considered when clinically appropriate or when MRI is unavailable or unsuitable. Supplemental tests can also lead to false positives, additional procedures, contrast exposure, or radiation, depending on the test.

Breast Density
Breast density is determined from a mammogram, not by touch. Dense tissue can both increase breast cancer risk and make cancers harder to see on mammography. Density alone does not automatically mean that supplemental imaging is required. Discuss your overall risk, benefits, and limitations with your provider.

Suggested Screening Discussion Timeline

By Age 25
Complete a formal risk assessment, especially if you have a family history, known genetic variant, or prior chest radiation.

Ages 25–29
Some high-risk patients may begin annual breast MRI during their 20s. The starting age depends on the risk factor and applicable guideline.

Age 30
Many screening plans for high-risk patients add annual mammography by about age 30. Some clinicians stagger MRI and mammography, but this approach is not required for everyone.

Age 40 and Beyond
National guidelines differ. The USPSTF recommends mammography every two years from ages 40–74. The ACR recommends annual screening beginning at age 40. The American Cancer Society allows annual screening at ages 40–44, recommends annual screening at ages 45–54, and permits annual or biennial screening beginning at age 55. Continue screening while early detection remains beneficial.

At Any Age
New symptoms, such as a lump, nipple discharge, skin changes, or persistent focal pain, require clinical evaluation and should not wait for routine screening. Dense breasts, a prior breast cancer, atypical biopsy findings, or other risk factors may support additional imaging after shared decision-making with your medical provider.

Your screening plan should reflect your age, health, personal preferences, and complete risk profile. Review it regularly with a qualified health care professional as your history or medical guidance changes.

Managing Scanxiety
Anxiety before imaging is not uncommon. These steps may help:
• Ground: Use slow, paced breathing for three to five minutes.
• Prepare: Follow the facility’s instructions. For mammography, avoid deodorant, powder, lotion, or perfume on the breasts or underarms on the day of the examination.
• Share your concerns: Working with your technologist can help alleviate your concerns.
• Support: Bring a trusted person, if permitted, and plan calming audio for the commute or waiting room.
• Reframe: Remind yourself, “This appointment is an important step in caring for my future health.”

If you require a follow-up visit, your first instinct might be to panic. Please take a deep breath. Callbacks are a routine part of screening mammography.

Educational Notice: This material is for general education only and is not medical advice, diagnosis, or a substitute for individualized care. Screening recommendations vary among organizations and may change. Consult a qualified health care professional about your specific risks, symptoms, testing options, and screening schedule.

Primestin Care offers a relationship-based approach focused on early detection, ongoing support, and long-term wellness. They use a membership-based model, meaning members pay the same predictable monthly fee for their care, helping them avoid surprise bills, deductibles, and complicated claims. Your membership connects you with medical providers, mental health support, and a care team who can coordinate appointments, specialist referrals, in-person visits, and more. For additional information or to schedule an appointment, visit primestin.care or call 435-659-3869.

Health & Fitness

Jayson Malufau, Southern Utah Health and Wellness Magazine

ABOUT THE AUTHOR: Dr. Jayson Malufau, DO, serves as Medical Director of Primestin Care, a Direct Primary Care practice that expands access to healthcare through a combination of in-person care in Southern Utah and flexible virtual appointments available in multiple states. Passionate about preventive medicine and addressing the root causes of disease, Dr. Malufau partners closely with patients to build practical, sustainable lifestyle habits that support long-term health and help prevent chronic illness. Outside of medicine, he enjoys exploring the outdoors and spending time with his family. Learn more at Primestin.care.